ESC

Zhang Tao Lab

Bioinformatics, Epigenetics and Genomics, Chengdu Institute of Biology, Chinese Academy of Sciences

We specialize in developing and applying DNA Large Language Models (LLMs) for plant genome analysis. Our lab is at the forefront of applying foundation models to decode complex DNA sequences, predict regulatory elements, and accelerate crop improvement. We build and maintain PDLLMs, a suite of open-source plant DNA language models for the research community. Our work spans from fundamental algorithm development to real-world applications in genomics, epigenetics, and genome engineering.

Featured: DNA Large Language Models

PDLLMs — Plant DNA Large Language Models published in Molecular Plant. Foundation models for analyzing plant genomes.

DNALLM-Suite — A unified toolkit for fine-tuning and inference with DNA Language Models. CLI, UI, and MCP support. Website

About the Lab

Our laboratory specializes in DNA Large Language Models and their applications in plant science. We develop and apply foundation models to understand, predict, and engineer plant genomes. Our work bridges the gap between cutting-edge AI and fundamental biology, spanning computational genomics, epigenetics, and genome editing. We are committed to building open-source tools that accelerate scientific discovery in the era of AI-driven biology.

Zhang Tao Lab

Bioinformatics, Epigenetics and Genomics

Chengdu Institute of Biology, Chinese Academy of Sciences

News

Latest
DNALLM-Suite — A unified toolkit for fine-tuning and inference with DNA Language Models. Learn more →
May 2026
May 2026
Glycosylase-mediated genome editing published in Science Bulletin.

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